Generic Name
Indication
Date Approved*
Autologel
Chronic Wounds
9/2007
Becaplermin (Regranex) Gel
Diabetic Foot Ulcers
12/1997
Graftskin (Apligraf)
Venous Leg Ulcers
5/1998
Graftskin (Apligraf)
Diabetic Foot Ulcers
6/2000
Hyperbaric Oxygen (HBO)
Enhancement of Healing in Selected Problem Wounds (e.g. Hypoxic Wounds)
Acute Traumatic Ischemias
Necrotizing Soft Tissue Infections
Refractory Osteomyelitis
Radiation Inhury to Soft Tissue and Bone
Compromised Skin Grafts and Flaps
Thermal Burn Injuries
Others: Decompression Sickness, Air/Gas Embolism, Carbon Monoxide / Cyanide Poisoning, Severe Anemia, Intracranial Abscess, Central Retinal Artery Occlusion, Clostridial Myositis/Myonecrosis
Acute Traumatic Ischemias
Necrotizing Soft Tissue Infections
Refractory Osteomyelitis
Radiation Inhury to Soft Tissue and Bone
Compromised Skin Grafts and Flaps
Thermal Burn Injuries
Others: Decompression Sickness, Air/Gas Embolism, Carbon Monoxide / Cyanide Poisoning, Severe Anemia, Intracranial Abscess, Central Retinal Artery Occlusion, Clostridial Myositis/Myonecrosis
Cryopreserved Dermal Substitute
Diabetic Foot Ulcers
9/2001
Negative Pressure Therapy (V.A.C.)
Promotion of Wound Healing
Partial-Thickness Burns
Venous Ulcers
Partial-Thickness Burns
Venous Ulcers
3/1995
12/2002
5/2010
12/2002
5/2010
Porcine Small Intestines Submucosa (OASIS Wound Matrix)
Partial and Full-thickness Wounds; Pressure Ulcers; Venous Leg Ulcers; Chronic Vascular Ulcers; Diabetic Foot Ulcers; Traumatic and Surgical Wounds
1/2000
*Approved by the U.S. FDA through NDA, PMA, or 510(k)